OxyR-Dependent Transcription Response of Sinorhizobium meliloti to Oxidative Stress
نویسندگان
چکیده
منابع مشابه
Formate-dependent autotrophic growth in Sinorhizobium meliloti.
It was found that S. meliloti strain SmA818, which is cured of pSymA, could not grow on defined medium containing only formate and bicarbonate as carbon sources. Growth experiments showed that Rm1021 was capable of formate/bicarbonate-dependent growth, suggesting that it was capable of autotrophic-type growth. The annotated genome of S. meliloti Rm1021 contains three formate dehydrogenase genes...
متن کاملRole of oxyR from Sinorhizobium meliloti in regulating the expression of catalases.
The process of symbiotic nitrogen fixation results in the generation of reactive oxygen species such as the superoxide anion (O2-) and hydrogen peroxide (H2O2). The response of rhizobia to these toxic oxygen species is an important factor in nodulation and nitrogen fixation. In Sinorhizobium meliloti, one oxyR homologue and three catalase genes, katA, katB, and katC were detected by sequence an...
متن کاملDisruption of sitA compromises Sinorhizobium meliloti for manganese uptake required for protection against oxidative stress.
During the initial stages of symbiosis with the host plant Medicago sativa, Sinorhizobium meliloti must overcome an oxidative burst produced by the plant in order for proper symbiotic development to continue. While identifying mutants defective in symbiosis and oxidative stress defense, we isolated a mutant with a transposon insertion mutation of sitA, which encodes the periplasmic binding prot...
متن کاملIdentification of novel Sinorhizobium meliloti mutants compromised for oxidative stress protection and symbiosis.
Employing a novel two-part screen, we identified Sinorhizobium meliloti mutants that were both sensitive to hydrogen peroxide and symbiotically defective on the host plant Medicago sativa. The mutations affect a wide variety of cellular processes and represent both novel and previously identified genes important in symbiosis.
متن کاملThe katA catalase gene is regulated by OxyR in both free-living and symbiotic Sinorhizobium meliloti.
The characterization of an oxyR insertion mutant provides evidences that katA, which encodes the unique H2O2-inducible HPII catalase, is regulated by OxyR not only in free-living Sinorhizobium meliloti but also in symbiotic S. meliloti. Moreover, oxyR is expressed independently of exogenous H2O2 and downregulates its own expression in S. meliloti.
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2018
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.00622-17